Autoinflammatory disorders (AID)


The autoinflammatory disorders are a group of diseases that, in their purest forms, manifest as recurrent fevers, high acute phase responses and a proclivity for inflammation of skin, joints, serosal surfaces and other organ involvement including the nervous system. These disorders lack the classical characteristics of autoimmune diseases such as high-titer autoantibodies. The innate immune system plays the primary pathophysiologic role in autoinflammatory diseases and in fact, these diseases are synonymous with dysregulation of the cells and molecular cascades intrinsic to innate immunity.

Reference centers

Center Country City
AOU Senese, SIENA Italy Siena
Naples AOU Federico II Italy Naples
Milan Fondazione IRCCS CA'Granda Ospedale Maggiore Policlinico Italy Milano
General Hospital of Athens "LAIKO" Greece Athens
Universitätsklinikum Würzburg Germany Würzburg
Tübingen University Clinic Germany Tübingen
Dresden University Hospital Germany Dresden
Berlin Charite Universitätsmedizin Germany Berlin
Assistance Publique-Hôpitaux de Paris, Hôpital Tenon France Paris
Helsinki University Hospital Finland Helsinki
Gent University Hospital Belgium Gent
Tallaght University Hospital Ireland Tallaght
Radboud University Medical Center Nijmegen Netherlands Nijmegen
Pomnik-Centrum Zdrowia Dziecka Poland Warszaw
Centro Hospitalar Universitário Lisboa Norte Portugal Lisbon
Sant Joan de Déu & Hospital Clínic de Barcelona Spain Barcelona
Hospital Universitario La Paz Spain Madrid
Sahlgrenska University Hospital Sweden Göteborg
Hospices Civils de Lyon France Lyon
Hospital Centre of Luxembourg Luxembourg Luxembourg
Mater Dei Hospital Malta Valetta
Semmelweis University Hungary Budapest
Rigshospitalet Copenhagen University Denmark Copenhagen
Aarhus University Hospital Denmark Aarhus
University Hospital Centre Zagreb Croatia Zagreb
Medical University Innsbruck Austria Innsbruck
Pauls Stradins Clinical University Hospital Latvia Riga
Karolinska University Hospital Sweden Stockholm
Erasmus University Medical Center Netherlands Rotterdam
UMC Groningen Netherlands Groningen
Spedali Civili Brescia Italy Brescia
Pediatric Hospital Bambino Gesù, Rome Italy Rome
IRCCS Institute Giannina Gaslini Italy Genoa
UMC Utrecht Netherlands Utrecht
Foundation IRCCS Polyclinic San Matteo Italy Pavia
Universitätsklinikum Münster Germany Münster
Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades France Paris
Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre France Paris
Klinikum der Universität München Germany Munich
University Hospital Leuven Belgium Leuven
General University Hospital in Prague Czech Rep. Prague
Great Ormond Street / Royal Free Hospitals* UK London
The Leeds Teaching Hospitals NHS Trust* UK Leeds
Barts Health NHS Trust* UK London